Targeted Degraders

Comprehensive services to support all steps of degrader discovery and development

Targeted Protein Degradation is a powerful strategy that leverages endogenous cellular machineries to induce the specific degradation of a protein of interest (often via leveraging E3 ubiquitin ligase complexes and their target recognition subunits, such as CRBN or VHL). We offer a range of services to support degrader discovery and development, from the early stages of target selection through screening and preclinical characterization. By coupling our powerful high-throughput screening services with deep proteomic insights, we enable the efficient discovery and development of these potent therapeutics.