Non-Covalent Binding Assays
Covalent Binding Assays
Proteomics & Chemoproteomics
Small Molecule Analysis
Oligo Analysis
Data Products
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Target Discovery & Validation
Lead Generation
Lead Selection & Optimization
Preclinical Studies
Biomarker Discovery, Development & Analysis
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Radiotherapeutics
Molecular Glues
Targeted Degraders
Covalent Drugs
DNA- and RNA-Targeting Drugs
Oligonucleotide Therapeutics
Kinase Inhibitors
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Oncology
Immunology
Neuroscience
Metabolic Disease
Infectious Disease
Rare Diseases
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ProteomeScout™
PlasmaScout™
QuantScout™
TurnoverScout™
Protein Turnover Atlas™
SignalingScout™
UbiScout™
DecryptM
TargetScout™
PhotoTargetScout™
KinomeScout™
CysScout™
SideScout™
NucleoBeads™
SurfaceScout™
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RapidFire-MS
ICP-MS
Orbitrap Astral Zoom
Orbitrap Ascend
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Project Management
Compound Management & Chemical Libraries
Screening Laboratory
Biochemistry & Chemical Biology
Cell & Molecular Biology
MS-based Proteomics
Computational Biology
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Biomarker Discovery, Development & Analysis
A biomarker refers to any measurable indicator that signifies a particular physiological process, disease state, or biological condition. Biomarkers can serve predictive, diagnostic, or prognostic roles and have significant value in both preclinical and clinical contexts. Pharmacodynamic biomarkers are used to measure the reactions of biological systems to pharmacological perturbations and are critical to demonstrating drug efficacy. Molecular biomarkers are often proteins but can also be lipids, sugars, and other biomolecules.
Our services enable unbiased biomarker discovery, targeted biomarker discovery and development, and biomarker analysis of 100s to 10,000s of samples. We offer a flexible suite of quantitative multiplexed MS-based assays that can be tailored to project-specific requirements, ensuring superior identification and profiling of relevant biomarker candidates.
Over the past 10+ years, we have developed targeted assays for many important protein biomarkers, such as cytokines and peptide hormones, oncogenes, protein kinases, immuno-oncology-related proteins, as well as signaling sign-posts and numerous other classes of biomolecules.
