Target Discovery & Validation

Target discovery is the first step in the drug discovery and development pipeline. In this stage, disease-relevant factors are identified, explored, characterized, and validated to assess their value as drug targets. These factors can include proteins, protein complexes, DNA and RNA molecules, and other biomolecules.

Effective target discovery requires a global understanding of disease biology, as well as relevant biological models. As part of target discovery efforts, scientists must also evaluate the feasibility of different therapeutic modalities to determine how best to interfere with disease processes. This stage of the drug discovery process involves the synthesis of diverse data, often from a variety of experiments or sources, in order to comprehensively characterize the target landscape and inform subsequent research efforts.

We accelerate the target discovery process by providing services to support:

Mechanistic understanding and understanding of disease mechanisms
Biological model characterization
Target identification
Target validation
Modality selection
Assay development
Evaluation of tool compounds and chemical probes

Explore Other Phases

Our end-to-end service pipeline supports all phases of drug discovery and development.

Lead Generation
Leverage high-throughput screening to discover lead compounds.
Lead Selection & Optimization
Prioritize potential leads and optimize their activity
Preclinical Studies
Comprehensively characterize drug activity, efficacy, and more
Biomarker Discovery, Development & Analysis
Identify and profile biomarkers with predictive, diagnostic, and prognostic value